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Fig. 7 | Molecular Neurodegeneration

Fig. 7

From: MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease

Fig. 7

PTGDS mRNA and protein expression between Tg-Mlkl+/+ and Tg-Mlkl−/− mice. a. The qRT-PCR results of PTGDS in the SN region of Tg-Mlkl+/+ and Tg-Mlkl−/− mice. b-c. Representative immunostaining for PTGDS in the cortex, striatum, and SN regions of Tg-Mlkl+/+ and Tg-Mlkl−/− mice (b). The whole-brain sections were shown in solid rectangles. The dashed rectangle regions were zoomed in and shown in the middle. Scale bars, 200 μm. The quantification results of PTGDS are shown in c. All data are representative of three independent experiments. The error bars represented the standard deviations (SD). *** p < 0.001, **** p < 0.0001, ns, no significance

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