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Fig. 8 | Molecular Neurodegeneration

Fig. 8

From: MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease

Fig. 8

The subcluster-specific analysis identifies specific and functional cell subclusters after MLKL deficiency in the A53T transgenic mice. a, c, e. UMAP visualization of subclusters of neurons (a), microglia (c), and astrocytes (e). The frequency distribution of each subcluster between the Tg-Mlkl+/+ and Tg-Mlkl−/− mice was shown at the bottom. b, d, f. Significantly enriched genes in the neurons (b), microglia (d), and astrocyte subclusters (f)

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