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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

Fig. 6

Mendelian randomization (MR) analyses for CSF sTREM2 on AD risk. A Scatter plot of SNP effects on outcome against SNP effects on exposure. The lines represent the causal estimate using 5 method: MR Egger, Inverse variance weighted (IVW), Simple mode, Weighted mode, and Weighted median. B Results of MR analyses for the different MR models. C Box plots of CSF sTREM2 Z Score by four cohorts and AT status

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