Table 1 Characteristics of sample by cohorts for EURs participants
Cohort | N | Age (mean ± SD) | Female (%) | APOE ε4+ (%) | Cases (%) | A+T- (%) | A+T+ (%) | sTREM2 |
|---|---|---|---|---|---|---|---|---|
Knight ADRC | 797 | 71.36 ± 8.65 | 425 (53.32 ) | 314 (39.4) | 178 (22.33) | 145 (21,61) | 149 (21.85) | 0.36 ± 0.937k |
ADNI | 676 | 73.75 ± 7.47 | 283 (41.86 ) | 342 (50.59) | 512 (75.74) | 182 (29.07) | 262 (41.85) | -0.3 ± 0.947k |
ACE | 435 | 71.95 ± 8.28 | 257 (59.08 ) | 156 (35.86) | 238 (54.71) | 61 (17.94) | 186 (54.71) | 0.08 ± 0.947k |
Barcelona-1 | 187 | 68.82 ± 7.38 | 90 (48.13 ) | 77 (41.18) | 59 (31.55) | 8 (12.90) | 52 (83.87) | 0.07 ± 1.087k |
DIAN | 172 | 39.89 ± 10.64 | 92 (53.49 ) | 48 (27.91) | 118 (68.6) | 24 (15.29) | 54 (34.39) | -0.7 ± 0.927k |
PPMI | 779 | 61.12 ± 9.33 | 330 (42.36 ) | 174 (22.34) | 460 (59.05) | NA | NA | 0.01 ± 0.995k |
VMAP | 135 | 72.39 ± 6.42 | 42 (31.11 ) | 49 (36.3) | 51 (37.78) | NA | NA | 0.03 ± 0.96MSD |
Stanford ADRC | 169 | 69.73 ± 6.66 | 97 (57.4 ) | 68 (40.24) | 46 (27.22) | 17 (17.35) | 22 (22.45) | 0.12 ± 1.005k |