Fig. 3
From: Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease
Brain age associations with amyloid biomarkers (A & B), pTau biomarkers (C & D), neurodegeneration biomarkers (E & F), and cognition (G & H). Solid colored lines and shaded regions reflect regression fits and confidence intervals derived from a linear regression model for specific groups. Dashed black lines and grey regions reflect linear regression fits in the full sample. Dotted horizontal lines reflect perfect age prediction. Dotted vertical lines reflect positivity thresholds for PIB PET and CSF Aβ42/40. Pearson’s correlation coefficient is reported for each specific group