Table 1 Demographic information for the sample

Age

436

0.000

0.79

Mean (SD)

37.5 (10.6)

34.3 (9.1)

46.3 (8.7)

Sex

436

0.75

Female

101 (56%)

104 (57%)

37 (50%)

Male

78 (44%)

79 (43%)

37 (50%)

Education

436

0.007

0.030

Mean (SD)

15.0 (2.8)

14.8 (2.7)

13.7 (3.1)

Self-Selected Race

436

0.69

Aboriginal Australian or Torres Strait Islander*

< 5

< 5

< 5

American Indian or Alaska Native*

< 5

< 5

< 5

Asian*

5 (2.8%)

< 5

< 5

Black or African American*

< 5

< 5

< 5

Hispanic or Latinx*

< 5

< 5

< 5

Middle Eastern or North African*

< 5

< 5

< 5

Native Hawaiian or Other Pacific Islander*

< 5

< 5

< 5

White

152 (85%)

155 (85%)

64 (86%)

More than one race

14 (7.8%)

11 (6.0%)

4 (5.4%)

Unknown

5 (2.8%)

10 (5.5%)

2 (2.7%)

CDR

436

< 0.001

0

179 (100%)

183 (100%)

0 (0%)

0.5

0 (0%)

0 (0%)

44 (59%)

1

0 (0%)

0 (0%)

26 (35%)

2

0 (0%)

0 (0%)

4 (5.4%)

EYO

436

0.003

0.16

Mean (SD)

-11.0 (11.4)

-14.3 (9.0)

1.4 (5.7)

APOE

436

0.86

ε4-

124 (69%)

124 (68%)

52 (70%)

ε4+

55 (31%)

59 (32%)

22 (30%)

Variant

436

0.45

APP

38 (21%)

38 (21%)

13 (18%)

PSEN1 Codon < 200

55 (31%)

48 (26%)

23 (31%)

PSEN1 Codon 200+

65 (36%)

75 (41%)

37 (50%)

PSEN2

21 (12%)

22 (12%)

1 (1.4%)