Table 1 Clinical and demographic characteristics of the TRIAD cohort
Young (N = 23) | CU (N = 74) | MCI (N = 36) | AD (N = 24) | OND (N = 16) | Overall (N = 173) | |
|---|---|---|---|---|---|---|
Sex | ||||||
Female, n (%) | 15 (65.2%) | 45 (60.8%) | 19 (52.8%) | 11 (45.8%) | 10 (62.5%) | 100 (57.8%) |
Male, n (%) | 8 (34.8%) | 29 (39.2%) | 17 (47.2%) | 13 (54.2%) | 6 (37.5%) | 73 (42.2%) |
Age, years | ||||||
Mean (SD) | 23.2 (2.58) | 69.7 (8.17) | 71.2 (7.47) | 63.1 (6.69) | 64.7 (8.33) | 62.5 (17.3) |
Education, years | ||||||
Mean (SD) | 17.2 (2.40) | 14.7 (3.53) | 15.2 (3.11) | 15.1 (3.34) | 13.8 (3.62) | 15.1 (3.38) |
MMSE | ||||||
Mean (SD) | 29.8 (0.52) | 29.1 (1.04) | 28.1 (1.74) | 20.6 (5.56) | 25.9 (5.58) | 27.5 (4.09) |
APOEε4 carriers | ||||||
Noncarriers, n (%) | 16 (69.6%) | 50 (67.6%) | 20 (55.6%) | 7 (29.2%) | 13 (81.3%) | 106 (61.3%) |
Carriers, n (%) | 7 (30.4%) | 24 (32.4%) | 16 (44.4%) | 17 (70.8%) | 3 (18.8%) | 67 (38.7%) |
Neocortical (18F)AZD4694 SUVR | ||||||
Mean (SD) | 1.20 (0.06) | 1.50 (0.42) | 2.03 (0.60) | 2.31 (0.510) | 1.23 (0.10) | 1.66 (0.57) |