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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Untargeted serum metabolomics reveals novel metabolite associations and disruptions in amino acid and lipid metabolism in Parkinson’s disease

Fig. 5

Volcano plot showing the combined fold change and p-values for 34 metabolites associated with PD in Shao et al, 2021 and detected in the current study LCMS data. The meta-analysis was performed using the amanida R package, designed to combine results when only the fold change, p-value, and sample size are available. P-values and log2FC are combined separately to assess validation on direction and magnitude of effect and significance separately, allowing metabolites associated in opposite directions to still be highlighted

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Molecular Neurodegeneration

ISSN: 1750-1326