Table 1 Sample Characteristics
|  | Total Sample (N = 364) |
|---|---|
Demographics | |
 Age of death, mean (SD) years | 62.48 (19.16) |
 Race, n (%) Black | 55 (15.1) |
 Education Level, n (%) | |
  Some High School | 2 (0.5) |
  High School Diploma/GED | 10 (2.7) |
  Some College | 72 (19.7) |
  College Degree | 190 (52.2) |
  More than College | 18 (4.9) |
  Graduate Degree | 72 (19.8) |
  APOE e4 carriers | 78 (36.3) |
Athletics | |
 Sport Played, n (%)a | |
  Football | 333 (91.5) |
  Ice hockey | 30 (8.2) |
  Wrestling | 29 (8.0) |
  Soccer | 28 (7.7) |
  Boxing | 27 (7.4) |
  Skiing | 2 (0.5) |
  Rugby | 12 (3.3) |
  Lacrosse | 10 (2.7) |
  Other | 6 (1.6) |
 Years of Football Play, mean (SD) | 13.71 (5.60) |
 Highest Level Football Played, n (%) | |
  Youth | 5 (1.5) |
  High school | 25 (7.5) |
  College | 115 (34.5) |
  Semi-Professional | 9 (2.7) |
  Professional | 179 (53.8) |
 Military history, n (%) | 89 (24.5) |
Medical Characteristics, n (%) | |
  Hypertension | 182 (50.8) |
  Obstructive sleep apnea | 91 (25.8) |
  Substance use treatment | 81 (22.4) |
Neuropathological Characteristics | |
 CTE stage, n (%) | |
  Stage I | 71 (19.5) |
  Stage II | 69 (19.0) |
  Stage III | 128 (35.2) |
  Stage IV | 96 (26.4) |
 Alzheimer’s disease, n (%) | 51 (14.0) |
 Braak Stage, n (%) | |
  0 | 75 (20.8) |
  I/II | 89 (24.7) |
  III/IV | 134 (37.1) |
  V/VI | 63 (17.5) |
 CERAD neuritic plaque score, n (%) | |
  None | 236 (64.8) |
  Sparse | 86 (23.6) |
  Moderate | 27 (7.4) |
  Severe | 15 (4.1) |
Thal Phase, n (%) | |
  0 | 162 (44.6) |
  1/2 | 54 (14.9) |
  3 | 49 (13.5) |
  4/5 | 98 (27.0) |
  Lewy body disease, n (%) neocortical | 35 (9.6) |
  Frontotemporal lobar degeneration, n (%) | 35 (9.7) |
  Motor neuron disease, n (%) | 13 (3.6) |
  No comorbid neurodegenerative pathology | 234 |