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Fig. 8 | Molecular Neurodegeneration

Fig. 8

From: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner

Fig. 8

Cytoscape and GSEA analyses using significantly altered genes (P < 0.01) in GV-971 treated male group compared with control. a Cytoscape analysis identified immunity pathway as a major impacted pathway associated with lower DEGs (P < 0.01) in GV-971-treated male compared with control. Most enriched genes are highlighted in darker shade. b Cytoscape analysis identified neuronal development pathway as a major impacted pathway associated with higher DEGs (P < 0.01) in GV-971 treated group compared with control. Most enriched genes are highlighted in darker shade. c GSEA enrichment results showed 9 significantly enriched gene sets out of 44 upregulated gene sets in Vehicle- treated male group compared with GV-971-treated male group

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Molecular Neurodegeneration

ISSN: 1750-1326