Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner

Table 3 GV-971 significantly alters microbiome bacterial species in male mice treated with 100 mg/kg compared with vehicle

Comparisons
Male Ctrl vs Male 100 mg/kg GV- 971	Increased in GV-971	Decreased in GV-971
	p__Actinobacteria;c__Actinobacteria; o__Bifidobacteriales;f__Bifidobacteriaceae; g__Bifidobacterium;s__Bifidobacterium pseudolongum	p__Firmicutes;c__Clostridia; o__Clostridiales;f__Ruminococcaceae; g__Anaerotruncus;s__Anaerotruncus sp G32012
	p__Firmicutes;c__Erysipelotrichia; o__Erysipelotrichales;f__Erysipelotrichaceae; g__Faecalibaculum;s__Faecalibaculum rodentium	p__Proteobacteria;c__Deltaproteobacteria; o__Desulfovibrionales;f__Desulfovibrionaceae; g__Desulfovibrio;s__Desulfovibrio sp ABHU2SB
	p__Proteobacteria;c__Betaproteobacteria; o__Burkholderiales;f__Sutterellaceae; g__Parasutterella;s__Parasutterella excrementihominis	p__Bacteroidetes;c__Bacteroidia; o__Bacteroidales;f__Rikenellaceae; g__Alistipes;s__Alistipes onderdonkii
		p__Firmicutes;c__Clostridia; o__Clostridiales;f__Lachnospiraceae; g__Blautia;s__Ruminococcus gnavus
		p__Firmicutes;c__Clostridia; o__Clostridiales;f__Ruminococcaceae; g__Ruminiclostridium;s__Clostridium leptum

ISSN: 1750-1326