Fig. 7
Longitudinal plasma NTA-tau association with baseline Aβ status. Longitudinal plasma NTA-tau changes classified by baseline Aβ status (negative, blue; positive, red) in in cognitively unimpaired (A) and impaired participants (B) from BioFINDER-1. Plasma NTA-tau levels were used as outcome in linear mixed models with the interaction between Aβstatus and time as predictor. Age and sex were included as covariates. Aβ-status was based on CSF Aβ42/40 levels. Standardized β (βstd) and p-values of the interaction term are shown in the plots. *: p < 0.05; **: p < 0.01; ***: p < 0.001. Abbreviations: Aβ, amyloid-β; CSF, cerebrospinal fluid