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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Melatonin: a ferroptosis inhibitor with potential therapeutic efficacy for the post-COVID-19 trajectory of accelerated brain aging and neurodegeneration

Fig. 1

General theme of ferroptosis. Ferroptosis is an iron-dependent cell death that disrupts the integrity of cell membranes. Lipid peroxidation is the executer of ferroptosis with three main prerequisites: high levels of reactive oxygen species (ROS) and redox labile iron and compromised lipid peroxide repair systems. LOO: lipid peroxides, LOOH: lipid hydroperoxides

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