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Figure 5 | Molecular Neurodegeneration

Figure 5

From: Intracellular amyloid formation in muscle cells of Aβ-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

Figure 5

C. elegans that express Aβ are resistant to Cu2+ toxicity. A. Control (open circles) and Aβ wt expressing animals (black circles) were exposed to a range of CuCl2 (A), CdCl2 (C), and ZnCl2 (D) concentrations in liquid K medium for 24 h. The number of worms that remained alive was determined under a stereoscope by visual inspection. The experiments were performed in triplicate. Data are means ± S.E. **p < 0.01; ***p < 0.001. B. Survival curves of control worms and Aβ worms cultured on 150 μM CuCl2. Comparison of survival curves using the Log-rank (Mantel-Cox) test yielded a p value of 0.0066 (n = 138).

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