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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice

Fig. 1

OHSCs maintain hippocampal architecture and express a full complement of different cell types. a, b 7-week old WT (a) and TgCRND8 (b) slices stained for Calbindin (green Alexa-488) and Tuj1 (red Alexa-568). Arrowheads show axons projecting from the dentate gyrus c, d 5-week old WT (c) and TgCRND8 (d) slices showing microglia (Iba1- green Alexa 488) and nuclei (Hoechst- blue) e, f 7-week old WT (e) and TgCRND8 (f) slices showing astrocytes (GFAP-red Alexa568) and nuclei (Hoechst-blue). Image locations, where appropriate, are denoted by the red ring on the hippocampus diagram inset in each panel

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Molecular Neurodegeneration

ISSN: 1750-1326