Table 1 Demographic, cognitive and pathological characteristics^a of MAP participants included in the present study

 Female, no. (%)

105 (70%)

40 (78%)

27 (64%)

38 (67%)

 Age at death, years

88.7 ± 6.3

86.7 ± 6.7

88.1 ± 6.8

90.9 ± 4.7

 Education, years

14.6 ± 2.9

13.9 ± 2.5

15.0 ± 2.8

15.0 ± 3.3

 Race, no. W:AA

146:4

49:2

41:1

56:1

  APOE ε4 carrier, no. (%)

33 (22%)

7 (14%)

11 (26%)

15 (26%)

 PMI, hours

6.6 ± 3.8

6.2 ± 2.1

7.6 ± 5.6

6.2 ± 3.1

 Global cognition score

−0.77 ± 1.01

0.10 ± 0.39

−0.47 ± 0.43

−1.80 ± 0.78

 MMSE

21.9 ± 8.2

27.7 ± 1.9

24.9 ± 4.6

14.4 ± 8.1

 Macroinfarcts, no (%)^b

45 (30%)

10 (20%)

15 (36%)

20 (35%)

 Lewy bodies, no (%)^b

25 (17%)

4 (8%)

1 (2%)

20 (35%)

 Hippocampal sclerosis, no (%)^b

14 (9%)

0 (0%)

4 (10%)

10 (18%)

 Arteriolosclerosis^b

1.39 ± 0.87

1.24 ± 0.84

1.38 ± 0.82

1.53 ± 0.93

 Amyloid plaques^c

5.3 ± 5.9

2.9 ± 3.3

5.5 ± 6.5

7.3 ± 6.5

 Tangles^c

1.1 ± 3.0

0.4 ± 1.7

1.1 ± 3.0

1.8 ± 3.7