Molecular Neurodegeneration: Basic biology and disease pathways

Decoding Alzheimer’s in the age of genome-wide analyses

Rudolph E Tanzi

Molecular Neurodegeneration 2013 8(Suppl 1):O1

Published on: 13 September 2013

Functional genetics – an approach to mechanisms in Alzheimer’s disease

Mikko Hiltunen

Molecular Neurodegeneration 2013 8(Suppl 1):O3

Published on: 13 September 2013

Role of APP in neuronal function

Hui Zheng

Molecular Neurodegeneration 2013 8(Suppl 1):O4

Published on: 13 September 2013

The biological function of β-secretase

Christian Haass

Molecular Neurodegeneration 2013 8(Suppl 1):O5

Published on: 13 September 2013

Proteomics in neurons and animals: substrates and therapeutic potential of alpha-and beta-secretase

Stefan Lichtenthaler

Molecular Neurodegeneration 2013 8(Suppl 1):O6

Published on: 13 September 2013

BACE1, the Alzheimer’s beta-secretase enzyme, in health and disease

Robert Vassar

Molecular Neurodegeneration 2013 8(Suppl 1):O7

Published on: 13 September 2013

Regulation of dynamic BACE1 trafficking in neurons

Virginie Buggia-Prévot, Celia G Fernandez, Sean Riordan, Kulandaivelu S Vetrivel, Vinod Udayar, Aureliane Elie, Margaret Lefkow, Jelita Roseman, Xavier Meckler, Sohinee Bhattacharyya, Manju George, Jack Waters, Vytautas P Bindokas, Angèle T Parent, Lawrence Rajendran, Hamid Band…

Molecular Neurodegeneration 2013 8(Suppl 1):O8

Published on: 13 September 2013

Endogenous and exogenous regulation of gamma-secretase

Yueming Li

Molecular Neurodegeneration 2013 8(Suppl 1):O10

Published on: 13 September 2013

Function and dysfunction of presenilin in Alzheimer’s disease

Jie Shen

Molecular Neurodegeneration 2013 8(Suppl 1):O11

Published on: 13 September 2013

Genetic analysis of neurodegeneration.. the end game

John Hardy

Molecular Neurodegeneration 2013 8(Suppl 1):O12

Published on: 13 September 2013

Regulation of mitochondrial function by PINK1, Parkin and DJ-1

Emilie Giaime and Jie Shen

Molecular Neurodegeneration 2013 8(Suppl 1):O13

Published on: 13 September 2013

Expanded G4C2 repeats linked to C9ORF72ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic

Youn-Bok Lee, Han-Jou Chen, João N Peres, Jorge Gomez, Valentina Sardone, Agnes L Nishimura, Emma Scotter, Caroline Vance, Maja Štalekar, Yoshitsugu Adachi, Claire Troakes, Jack Miller, Bradley Smith, Frank Hirth, Boris Rogelj, Corinne Houart…

Molecular Neurodegeneration 2013 8(Suppl 1):O14

Published on: 13 September 2013

In situstudies of protein aggregation kinetics with multiparametric and superresolution imaging

Gabriele Kaminski Schierle, Claire Michel, Eric Rees, Dorothea Pinotsi and Clemens Kaminski

Molecular Neurodegeneration 2013 8(Suppl 1):O15

Published on: 13 September 2013

Designing nanoparticles for delivery of neurotrophic proteins

Angelina Angelova, Borislav Angelov and Sylviane Lesieur

Molecular Neurodegeneration 2013 8(Suppl 1):O16

Published on: 13 September 2013

Novel non-carbohydrate O-GlcNAcase inhibitors with CNS drug properties as potential treatment for Alzheimer’s disease and tauopathies

Heike Hering, Danielle Graham, Solenne Ousson, Maud Neny, Audrey Gray, Brandy Giacomozzi, John Joyce, Vikram Dutt, Michael Busch, Andrew Cameron, Leslie Liu-Bujalski, Henry Yu, Hui Tian, Mark Shearman, Anna Quattropani, Bruno Permanne…

Molecular Neurodegeneration 2013 8(Suppl 1):O17

Published on: 13 September 2013

Super-resolution fluorescence imaging of intracellular mutant huntingtin protein reveals a population of fibrillar aggregates co-existing with compact perinuclear inclusion bodies

Steffen J Sahl, Lucien E Weiss, Lana Lau, Judith Frydman and WE Moerner

Molecular Neurodegeneration 2013 8(Suppl 1):O18

Published on: 13 September 2013

Vascular hypothesis of Alzheimer’s disease: role of apoE and apoE receptors

Guojun Bu, Chia-Chen Liu and Takahisa Kanekiyo

Molecular Neurodegeneration 2013 8(Suppl 1):O20

Published on: 13 September 2013

Prion-like aspects of cerebral amyloidosis

Mathias Jucker, Lan Ye and Sarah Fritschi

Molecular Neurodegeneration 2013 8(Suppl 1):O21

Published on: 13 September 2013

Secretases: potential and roadblocks on the way to therapy

Bart De Strooper

Molecular Neurodegeneration 2013 8(Suppl 1):O22

Published on: 13 September 2013

A novel mechanism underlying pathogenesis of Down syndrome

Xin Wang, Yingjun Zhao, Xiaofei Zhang, Ying Zhou, Barbara Ranscht, Fred H Gage, William C Mobley, Yun-wu Zhang, Stuart A Lipton, Wanjin Hong and Huaxi Xu

Molecular Neurodegeneration 2013 8(Suppl 1):O23

Published on: 13 September 2013