Skip to content


  • Correction
  • Open Access

Correction to: Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice

  • 1,
  • 2,
  • 3 and
  • 1Email author
Molecular Neurodegeneration201712:81

  • Received: 20 October 2017
  • Accepted: 20 October 2017
  • Published:

The original article was published in Molecular Neurodegeneration 2017 12:14


The original article [1] contains an error in the y-axes of Fig. 10a & b – the accidental omission of a μ symbol preceding the denoted units for both graphs means that incorrect units are displayed.
Fig. 10
Fig. 10

Adult-only lead exposure results in elevated blood lead levels and lead deposition in the brain. 8-week-old ApoE3- KI and ApoE4-KI male and female mice were exposed to 0.2% lead acetate for 12 weeks and then sacrificed. Blood and one brain hemisphere were collected at sacrifice and (a) blood lead and (b) brain lead levels were measured using ICPMS. Brightfield images of one brain hemisphere from a female (c) control and (d) lead-treated ApoE4-KI mouse after the 12 week lead exposure. Semi-quantitative measurement of lead in the brain of a (e) control and (f) lead-treated ApoE4-KI mouse using LA-ICP-MS. Two-way ANOVA with Fisher’s LSD post-test: n.s., not significant; ** p < 0.01; *** p < 0.001. Scale bars, 100 μm

As such, the authors would like to note that the correct units are μg/dL for Fig. 10a and μg/g for Fig. 10b.

The correct version of this figure is displayed below for reference too.



Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

Toxicology Program, Department of Environmental and Occupational Health Sciences, University of Washington, Box 357234, Seattle, WA 98195, USA
Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA
Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA


  1. Engstrom AK, et al. Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice. Mol Neurodegener. 2017;12(1):14. 10.1186/s13024-017-0155-2.View ArticlePubMedPubMed CentralGoogle Scholar


© The Author(s). 2017