A central event in Alzheimer's disease (AD) is the regulated intramembraneous proteolysis of the β-amyloid precursor protein (APP), to generate the β-amyloid (Aβ) peptide and the APP intracellular domain (AICD...
Authors:
Can Zhang, Preeti J Khandelwal, Ranjita Chakraborty, Trinna L Cuellar, Srikant Sarangi, Shyam A Patel, Christopher P Cosentino, Michael O'Connor, Jeremy C Lee, Rudolph E Tanzi and Aleister J Saunders
Citation:
Molecular Neurodegeneration
2007
2:15
Content type: Research article
Published on: 24 August 2007